Successful Treatment of Scleredema Diabeticorum With Tranilast: Three Case Reports
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Treatment of scleredema diabeticorum with tamoxifen.
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Scleredema is a rare condition of unknown pathogenesis. It is classically divided into three types, based on its association with postinfection (usually streptococcal), monoclonal gammopathy and diabetes mellitus (scleredema diabeticorum). Scleredema diabeticorum often has a subtle onset, persistent involvement and is refractory to therapies. Numerous therapies have been tried, with mixed and i...
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Scleredema, an unusual disorder of the skin, is associated with symmetric induration and thickening of the skin generally on the posterior neck and the upper back.1-4 Scleredema is classified. into two types, scleredema adultorum of Buschke and scleredema diabeticorum.4,5 Scleredema adultorum of Buschke is more commonly diagnosed in children, despite the term adultorum, and is 'usually preceded...
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Background. Scleredema adultorum, a connective tissue disorder of unknown aetiology, is characterized by a thickening of the reticular dermis in the upper back of the body that may decrease the mobility of the affected tissues. It has been reported in diabetic patients with poor metabolic control. Therapeutic options are limited with generally poor results. Case Report. 53-year-old white male w...
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Scleredema diabeticorum is a rare complication of diabetes, characterized by diffuse induration of the skin over the neck, shoulders, and upper trunk and arms, progressively leading to limited upper body motility and impaired respiratory function (1). Etiology is unknown, and histopathological findings include thickened dermis with abundant mucin deposition among large collagen bundles. No trea...
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ژورنال
عنوان ژورنال: Diabetes Care
سال: 2018
ISSN: 0149-5992,1935-5548
DOI: 10.2337/dc17-1994